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KMID : 0355420140380020090
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Journal of Korean Academy of Oral Health
2014 Volume.38 No. 2 p.90 ~ p.94
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Effect of bamboo salt on human gingival fibroblasts
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Oh Han-Na
Choi Choong-Ho
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Abstract
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Objectives: To evaluate the anti-inflammatory and cytotoxic activities of bamboo salt.
Methods: Cytotoxicity of bamboo salt and bay salt (0.01%, 0.1%, and 1%) was evaluated using MTT assay. In addition, secretion of the pro-inflammatory cytokines interleukin (IL)-1b and IL-6 from human gingival fibroblasts (HGFs) was measured after application of 0.01% and 0.1% concentrations by using real-time polymerase chain reaction.
Results: Bamboo salt and bay salt at 1% concentration were cytotoxic to HGFs at 24 h; however, no such effect was observed at 0.01% or 0.1%. Bamboo salt showed a relatively low inhibitory effect. IL-1b secretion was inhibited by a 0.1% solution of bamboo salt. IL-6 secretion was inhibited by both bamboo salt and bay salt at 0.1% concentration.
Conclusions: The above results suggest that bamboo salt inhibits the release of IL-1b and IL-6 from HGFs. Thus, bamboo salt may be a useful material for gingival inflammation.
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KEYWORD
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Bamboo salt, Human gingival fibroblast, IL-1b, IL-6
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